Single fibre electromyography in central core disease

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Single fibre electromyography in central core disease.

Single fibre electromyography in the extensor digitorum communis muscle was studied in five patients with central core disease. The average number of muscle fibre action potentials belonging to the same motor unit was higher in patients than in healthy subjects of the same age. The increase in motor unit fibre density is consistent with increased terminal innervation ratio described in other pa...

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Neuromuscular transmission in myasthenia gravis studied with single fibre electromyography.

Patients with myasthenia gravis have been investigated with single fibre electromyography. In all myasthenic muscles recordings were obtained where there was an increase of the jitter and occasional blocking of different degree of single fibre action potentials. The jitter is the variability at consecutive discharges in the time interval between action potentials from two muscle fibres from the...

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Central core disease

Central core disease (CCD) is an inherited neuromuscular disorder characterised by central cores on muscle biopsy and clinical features of a congenital myopathy. Prevalence is unknown but the condition is probably more common than other congenital myopathies. CCD typically presents in infancy with hypotonia and motor developmental delay and is characterized by predominantly proximal weakness pr...

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Single-polarisation mode in air-core holey fibre

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Single-fibre electromyography (SFEMG) at different firing rates in myasthenia with and without thymoma.

The single fibre EMG differences during motor axonal stimulation at different firing rates were studied in myasthenic patients: 15 with, and 15 without thymoma. 10 healthy volunteers were also examined. Conventional repetitive stimulation EMG as well as SFEMG during weak voluntary contraction and on 10 and 20Hz stimulation was performed in every patient. The mean jitter in the control group was...

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ژورنال

عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry

سال: 1979

ISSN: 0022-3050

DOI: 10.1136/jnnp.42.7.662